Covers all the important theories from the period 1250-1400, including "maiores" as well as "minores," and issues in a discussion of Marsilius of Inghen (d. ...

Die metaphysische Spekulation über die Natur der Ideen gilt als eines der wichtigsten philosophischen Themen bis weit ins 20. Jahrhundert hinein. Im Nachdenken über die Ideen hat die Metaphysik versucht, die unveränderlichen Prinzipien zu entdecken, die die Wirklichkeit ordnen und ihren intelligiblen Charakter erklären und begründen. Die Frage nach den Ideen liegt somit an der Basis des metaphysischen Denkens überhaupt, das nach der klassischen Bestimmung des Aristoteles als Wissenschaft von den Prinzipien und Ursachen des Seienden als solchen verstanden werden kann.

Parti INTRODUCTION Wittgenstein sometimes suggested looking on words as instruments, for example in the following passages from ...

Much ink has been spilt in consideration of the once pervasive reliance on military metaphors to depict the relationships between science and religion in the nineteenth century. This has resulted in historically sensitive treatments of secularization; and the realization that the relationship between science and religion was not a bloody war between intellectual nation states, but a protracted divorce of former partners. Moreover, historians of science have been encouraged to throw off the yoke of the internalism–externalism debate, and to explore (...) the cultural boundaries that impinged upon practitioners of a natural knowledge of the world. Within the historiography of nineteenth-century science, this has resulted in many new perspectives on science and natural knowledge in relation to cultural control and authority. (shrink)

Marsilius of Inghen’s Commentary on the Sentences evinces the history of Scholasticism between Ockham and Luther. The part edited here discusses the Trinity revealing new evidence on the debates among Realists and Nominalists at the Universities of Paris and Heidelberg.

In the recent past, several papers have pointed to the possibility that tumour removal generates a permissive environment in which tumour growth is potentiated. This phenomenon has been coined “perioperative tumour growth” and whilst it represents a departure in terms of our attitude to the surgical process, this concept was first hinted at by Paget1Sir James Paget (1814–1899) was a surgeon and physiologist who is widely held (along with Rudolph Virchow) to be the father of the science of pathology. Paget (...) described Paget's disease of the nipple as well as Paget's disease of bone. himself. Despite this, the time interval immediately before and after cancer surgery (i.e. the perioperative period) remains an underutilised interval during which chemotherapeutic regimens are rarely implemented. Herein, we present a summarised review of the literature that supports the concept that tumour removal may potentiate the growth of residual neoplastic disease. We also outline current knowledge regarding underlying mechanisms and in this manner highlight potential therapeutic entry points. Finally, we emphasise the urgent need for trials of agents that could protect patients against the harmful host–tumour interactions that may occur during the perioperative period. BioEssays 28: 433–437, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

In reading Wittgenstein one can, and for the most part perhaps should, treat the expression ‘language-game’ as a term of art, a more or less arbitrarily chosen item of terminology meaning something like ‘an actual or possible way of using words’. It would then be a fairly routine task to work out answers to such questions as what features of the ways a word is used are emphasized by this term of art, what philosophical purposes are served by the description (...) of primitive language-games or of variations on actual language-games, or in exactly what way those purposes are supposed to be served. (shrink)

Many people seem to find it quite impossible to doubt that if a person did not do something freely, then he can be neither praised nor blamed for doing it. This assumption is shared by people with very different views about freedom, determinism and moral responsibility. It is held by most ‘libertarians’, who, to preserve moral responsibility, reject determinism. It is held by ‘hard determinists’, who accept determinism and therefore reject moral responsibility; and it is held by ‘soft determinists’, who (...) accept determinism, but argue that determinism does not exclude any kind of freedom that is relevant to whether a person may be held responsible. (shrink)